General Medical Information About their Clinical Significance of Pneumonia

Inflammation from the lung is recognized as Pneumonia. Pneumonias may be caused by specific pathogens like Pneumococcus or Klebsiella or by mixed flora which get to the lungs attributable to aspiration of infected material from top of the respiratory passages, stomach or exterior. Messy group called aspiration pneumonia. Pneumococcal pneumonia is the commonest type in adults. pneumococcal vaccine

Other Organisms causing Pneumonia

Staphylococcal Pneumonia

This may appear far more frequently noticed in debilitated subjects and in hospitalized individuals. Respiratory viral infections predispose to staphylococcal pneumonia. Is definitely a dreaded complication in children with cystic fibrosis also in patients receiving immunosuppressant therapy. The organisms reach the lung along with the blood stream (Pyemia) or along the respiratory airways.

Clinical features: The onset is with mild symptoms, but soon the condition worsens in order to grave toxemia, purulent and blood stained sputum and cyanosis. The lesions are commonly multiple, giving rise to thin-walled abscesses. It may frequently spread to the pleura to generate emphysema or pyo-pneumothorax. Indication of lobar consolidation may cease evident. Diagnosis should be suspected from the clinical setting and the presence of toxemia fat out of proportion towards the pulmonary joins. Gram-staining of sputum and culture reveal the organisms. Mortality varies from 20-25%.
Treatment: Actually most strains of hospitalized-acquired staphylococci produce penicillinase. Hence penicillinase-resistant drugs such as Cephalothin, cloxacillin or vancomycin may be necessary. Early diagnosis and prompt treatment ensures treatment.

Klebsiella Pneumonia (Friedlander’s Pneumonia)

This can be a grave illness seen in patients above the age of 40 years. Debilitating diseases, alcoholism, and malnutrition predispose this problems. Common site of involvement is the posterior segment of the top of lobe. Problem sets with sudden chills, rigors, fever, dyspnea and cough with gelationous thick sputum streaked with maintain. The course may be subacuate or fulminant and fatal. Abscess formation is a common difficulty. Mortality is high, ranging around 30%.

Treatment

Once the condition is suspected, urgent treatment with Cephalexin 1g, 6h, intramuscular administration should be started. Gentamicin in a dose of 5-8mg/Kg possibly be added to be a second anti-biotic. Treatment may have to become continued for 2 weeks or maybe to ensure cure.

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